56682-25-8
Chemical Structure
(8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol
- CAS No.: 56682-25-8
- Formula:C20H34O2
- Molecular Weight:306.48
InChIKey: OOLRCVXXZSHYDM-ZWDFGCBGSA-N
SMILES: C[C@@]12[C@]3([H])[C@](O[C@@](C3)([H])[C@](C)(O)C=C)(CC[C@@]1([H])C(C)(CCC2)C)C
Biological Activity: (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol is a diterpene found in Abies georgei. (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol is a nuclear factor kappa B (NF-κB) inhibitor that inhibits TNFα-triggered NF-κB activity (IC50 = 8.7 μg/mL). (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol exhibits anti-inflammatory activity and can inhibit NO production. (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol shows significant cytotoxicity against tumor cells[1].
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(8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol | (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol is a diterpene found in Abies georgei. (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol is a nuclear factor kappa B (NF-κB) inhibitor that inhibits TNFα-triggered NF-κB activity (IC50 = 8.7 μg/mL). (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol exhibits anti-inflammatory activity and can inhibit NO production. (8R,12R,13R)-8,12-Epoxylabd-14-en-13-ol shows significant cytotoxicity against tumor cells. | |||||||||||||||||||||
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