574759-62-9

VAF347 Chemical Structure
574759-62-9

Chemical Structure

VAF347

  • CAS No.: 574759-62-9
  • Formula:C17H11ClF3N3
  • Molecular Weight:349.74

IUPAC Name: 4-(3-chlorophenyl)-N-(4-(trifluoromethyl)phenyl)pyrimidin-2-amine

InChIKey: XTKUZTBZRIJTFR-UHFFFAOYSA-N

SMILES: FC(C1=CC=C(NC2=NC=CC(C3=CC=CC(Cl)=C3)=N2)C=C1)(F)F

Biological Activity: VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14+CD11b+ monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects[1].

Cat. No. Product Name Purity Description Pricing
HY-135750
VAF347 99.75% VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14+CD11b+ monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References