583-91-5
583-91-5
Chemical Structure
2-Hydroxy-4-(methylthio)butyric acid
- CAS No.: 583-91-5
- Formula:C5H10O3S
- Molecular Weight:150.20
IUPAC Name: 2-hydroxy-4-(methylthio)butanoic acid
InChIKey: ONFOSYPQQXJWGS-UHFFFAOYSA-N
SMILES: O=C(C(CCSC)O)O
Biological Activity: 2-Hydroxy-4-(methylthio)butyric acid (2-Hydroxy-4-(Methylthio)-Butanoic Acid) is an orally active source of methionine. 2-Hydroxy-4-(methylthio)butyric acid reduces the expression of multiple mRNAs (BHMT, MTR, MAT1A, SAHH, and PCK1). 2-Hydroxy-4-(methylthio)butyric acid increases milk production in periparturient cows[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Hydroxy-4-(methylthio)butyric acid | 88.0% | 2-Hydroxy-4-(methylthio)butyric acid (2-Hydroxy-4-(Methylthio)-Butanoic Acid) is an orally active source of methionine. 2-Hydroxy-4-(methylthio)butyric acid reduces the expression of multiple mRNAs (BHMT, MTR, MAT1A, SAHH, and PCK1). 2-Hydroxy-4-(methylthio)butyric acid increases milk production in periparturient cows. | ||||||||||||||||||||
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References
- [1]. Fang Z, et al. Methionine metabolism in piglets Fed DL-methionine or its hydroxy analogue was affected by distribution of enzymes oxidizing these sources to keto-methionine. J Agric Food Chem. 2010 Feb 10;58(3):2008-14. [Content Brief]
- [2]. St-Pierre NR, et al. Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) and its isopropyl ester on milk production and composition by Holstein cows. J Dairy Sci. 2005 Jul;88(7):2487-97. [Content Brief]
- [3]. Noftsger SM, et al. Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) on microbial growth in continuous culture. J Dairy Sci. 2003 Aug;86(8):2629-36. [Content Brief]
- [4]. Piepenbrink MS, et al. Feeding 2-hydroxy-4-(methylthio)-butanoic acid to periparturient dairy cows improves milk production but not hepatic metabolism. J Dairy Sci. 2004 Apr;87(4):1071-84. [Content Brief]
- [5]. Zhang Q, et al. The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis. J Dairy Sci. 2016 Oct;99(10):8451-8460. [Content Brief]
