58329-72-9
Chemical Structure
2'-O-MB-cGMP sodium
Synonym(s): 2′-O-Monobutyryl-cGMP sodium
- CAS No.: 58329-72-9
- Formula:C14H17N5NaO8P
- Molecular Weight:437.28
IUPAC Name: sodium (4aR,6R,7R,7aR)-6-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-(butyryloxy)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide
InChIKey: JZWDPPBOSPGNFH-CRDPPMACSA-M
SMILES: O=C(NC(N)=N1)C2=C1N(C=N2)[C@@H]3O[C@H](CO4)[C@@H](OP4(O[Na])=O)[C@H]3OC(CCC)=O
Biological Activity: 2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium is a cyclic GMP-specific phosphodiesterase inhibitor with an I50 value of 35 µM. 2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium inhibits Ca2+ dependent phosphodiesterase hydrolysis using cAMP or cGMP as substrate[1].
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2'-O-MB-cGMP sodium | 2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium is a cyclic GMP-specific phosphodiesterase inhibitor with an I50 value of 35 µM. 2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium inhibits Ca2+ dependent phosphodiesterase hydrolysis using cAMP or cGMP as substrate. | |||||||||||||||||||||
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