58525-82-9
58525-82-9
Chemical Structure
L-Azatyrosine
- CAS No.: 58525-82-9
- Formula:C8H10N2O3
- Molecular Weight:182.18
IUPAC Name: (S)-2-amino-3-(5-hydroxypyridin-2-yl)propanoic acid
InChIKey: YOZSEGPJAXTSFZ-ZETCQYMHSA-N
SMILES: OC([C@@H](N)CC1=CC=C(O)C=N1)=O
Biological Activity: L-Azatyrosine is an antitumor Antibiotic. L-Azatyrosine is present in Streptomyces chibanensis. L-Azatyrosine inhibits the growth of K-ras-transformed cells without affecting wild-type cells. L-Azatyrosine exhibits anticancer activity against prostate cancer. L-Azatyrosine can be used in studies related to prostate cancer[1][2].
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L-Azatyrosine | L-Azatyrosine is an antitumor Antibiotic. L-Azatyrosine is present in Streptomyces chibanensis. L-Azatyrosine inhibits the growth of K-ras-transformed cells without affecting wild-type cells. L-Azatyrosine exhibits anticancer activity against prostate cancer. L-Azatyrosine can be used in studies related to prostate cancer. | |||||||||||||||||||||
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References
- [1]. Seton A W, et al. A revised synthesis of the antitumour antibiotic L-azatyrosine via 2-iodo-5-methoxypyridine[J]. Journal of Chemical Research, 2001, 2001(12): 546-548.
- [2]. WANG H U I P O, et al. Preparation and Antitumor Activities of b-Azatyrosinamides[J]. Journal of Food and Drug Analysis, 2000, 8(3).
