591778-83-5
591778-83-5
Chemical Structure
CP-610431
- CAS No.: 591778-83-5
- Formula:C30H37N3O2
- Molecular Weight:471.63
IUPAC Name: (R)-1'-(anthracene-9-carbonyl)-N,N-diethyl-[1,4'-bipiperidine]-3-carboxamide
InChIKey: TXUIRLUAKARNPD-XMMPIXPASA-N
SMILES: O=C([C@H]1CN(C2CCN(C(C3=C4C=CC=CC4=CC5=CC=CC=C35)=O)CC2)CCC1)N(CC)CC
Biological Activity: CP-610431 is a reversible, ATP-uncompetitive, isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor. CP-610431 inhibits ACC1 and ACC2 with IC50s of ~50 nM. CP-610431 can be used for the research of metabolic syndrome[1].
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CP-610431 | CP-610431 is a reversible, ATP-uncompetitive, isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor. CP-610431 inhibits ACC1 and ACC2 with IC50s of ~50 nM. CP-610431 can be used for the research of metabolic syndrome. | |||||||||||||||||||||
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References
- [1]. H James Harwood Jr, et al. Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. J Biol Chem. 2003 Sep 26;278(39):37099-111. [Content Brief]
