593278-77-4
593278-77-4
Chemical Structure
Guanylyltransferase
- CAS No.: 593278-77-4
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Guanylyltransferase]
Biological Activity: Guanylyltransferase (GTase) plays a central role in the three-step catalytic process of adding an m7GpppN cap cotranscriptionally to nascent mRNA (pre-mRNAs)[1][2].
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Guanylyltransferase | Guanylyltransferase (GTase) plays a central role in the three-step catalytic process of adding an m7GpppN cap cotranscriptionally to nascent mRNA (pre-mRNAs). | |||||||||||||||||||||
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References
- [1]. Garg G, et al. Structural insights into human co-transcriptional capping. Mol Cell. 2023 Jul 20;83(14):2464-2477.e5. [Content Brief]
- [2]. Chu C, et al. Structure of the guanylyltransferase domain of human mRNA capping enzyme. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10104-8. [Content Brief]
