594860-23-8
Chemical Structure
Evariquinone
- CAS No.: 594860-23-8
- Formula:C16H12O6
- Molecular Weight:300.26
IUPAC Name: 1,2,3-trihydroxy-8-methoxy-6-methylanthracene-9,10-dione
InChIKey: DCNMIRIWFDFXKU-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=CC(O)=C(C(O)=C13)O)=O)C=C(C=C2OC)C
Biological Activity: Evariquinone is an anthraquinone compound isolated from the endophytic fungus Colletotrichum sp. JS-0367 of mulberry. Evariquinone possesses direct antioxidant activity. It inhibits excessive phosphorylation of the JNK, ERK1/2 and p38 MAPK signaling pathways by suppressing ROS and Ca2+, thereby reducing neuronal apoptosis. Evariquinone can be used to study glutamate excitotoxicity-related neurological disorders (such as Alzheimer's disease, Parkinson's disease, cerebral ischemia, etc.)[1].
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Evariquinone | Evariquinone is an anthraquinone compound isolated from the endophytic fungus Colletotrichum sp. JS-0367 of mulberry. Evariquinone possesses direct antioxidant activity. It inhibits excessive phosphorylation of the JNK, ERK1/2 and p38 MAPK signaling pathways by suppressing ROS and Ca2+, thereby reducing neuronal apoptosis. Evariquinone can be used to study glutamate excitotoxicity-related neurological disorders (such as Alzheimer's disease, Parkinson's disease, cerebral ischemia, etc.). | |||||||||||||||||||||
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