60-02-6
60-02-6
Chemical Structure
Guanethidine sesquisulfate
- CAS No.: 60-02-6
- Formula:C10H22N4.1/2H2O4S
- Molecular Weight:247.34
SMILES: O=S(O)(O)=O.N=C(NCCN1CCCCCCC1)N.[0.5]
Biological Activity: Guanethidine sesquisulfate, an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sesquisulfate enters noradrenergic nerve terminals by the neuronal amine carrier[1][2].
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Guanethidine sesquisulfate | Guanethidine sesquisulfate, an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sesquisulfate enters noradrenergic nerve terminals by the neuronal amine carrier. | |||||||||||||||||||||
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References
- [1]. Mitchell JR, et al. Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA. 1967 Dec 4;202(10):973-6. [Content Brief]
- [2]. Nielsen GD. Guanethidine induced sympathectomy in the adult rat. I. Functional effects following subacute administration. Acta Pharmacol Toxicol (Copenh). 1977 Sep;41(3):203-8. [Content Brief]
