60945-03-1
60945-03-1
Chemical Structure
NK037
- CAS No.: 60945-03-1
- Formula:C15H8N2O2S
- Molecular Weight:280.30
InChIKey: LSXOUPJSDGCGMO-UHFFFAOYSA-N
SMILES: O=C1N(C2=NC3=C(C=CC=C3)S2)C(C4=CC=CC=C41)=O
Biological Activity: NK037 is a phthalimide derivative that exhibits multi-target enzyme inhibitory activity against urease, xanthine oxidase, and butyrylcholinesterase (BChE). NK037 inhibits urease with IC50 = 2.9 μM, xanthine oxidase with IC50 = 5.61 μM, and butyrylcholinesterase with IC50 = 9.49 μM. NK037 can form enzyme-ligand complexes with urease, xanthine oxidase, and thymidine phosphorylase. Urease-IN-26 can be used for metabolism-related research[1].
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NK037 | NK037 is a phthalimide derivative that exhibits multi-target enzyme inhibitory activity against urease, xanthine oxidase, and butyrylcholinesterase (BChE). NK037 inhibits urease with IC50 = 2.9 μM, xanthine oxidase with IC50 = 5.61 μM, and butyrylcholinesterase with IC50 = 9.49 μM. NK037 can form enzyme-ligand complexes with urease, xanthine oxidase, and thymidine phosphorylase. Urease-IN-26 can be used for metabolism-related research. | |||||||||||||||||||||
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