618865-88-6
618865-88-6
Chemical Structure
ST45177901
- CAS No.: 618865-88-6
- Formula:C26H16ClN3O4S3
- Molecular Weight:566.07
InChIKey: AFJDHUDRDUPQTC-UHFFFAOYSA-N
SMILES: O=C(C1=C(C(N(C1C2=CC=CS2)C3=NN=C(SCC4=CC=C(C=C4)Cl)S3)=O)O)C5=CC6=C(C=CC=C6)O5
Biological Activity: ST45177901 is a CC chemokine receptor 4 (CCR4) antagonist. The combination of ST45177901 and Sorafenib (HY-10201) effectively inhibits the chemotaxis of Treg cells via the CCL22/CCL17-CCR4 signaling pathway, thereby significantly suppressing the growth and metastasis of tumor cells. ST45177901 is applicable to liver cancer research[1].
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ST45177901 | ST45177901 is a CC chemokine receptor 4 (CCR4) antagonist. The combination of ST45177901 and Sorafenib (HY-10201) effectively inhibits the chemotaxis of Treg cells via the CCL22/CCL17-CCR4 signaling pathway, thereby significantly suppressing the growth and metastasis of tumor cells. ST45177901 is applicable to liver cancer research. | |||||||||||||||||||||
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