621-36-3
621-36-3
Chemical Structure
m-Tolylacetic acid
Synonym(s): 3-Methylbenzeneacetic acid
- CAS No.: 621-36-3
- Formula:C9H10O2
- Molecular Weight:150.18
IUPAC Name: 2-(m-tolyl)acetic acid
InChIKey: GJMPSRSMBJLKKB-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC=CC(C)=C1
Biological Activity: m-Tolylacetic acid (3-Methylbenzeneacetic acid) is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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m-Tolylacetic acid | 99.93% | m-Tolylacetic acid (3-Methylbenzeneacetic acid) is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules. | ||||||||||||||||||||
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m-Tolylacetic acid (Standard) | ≥98% | m-Tolylacetic acid (3-Methylbenzeneacetic acid) (Standard) is the analytical standard of m-Tolylacetic acid (HY-W053507). This product is intended for research and analytical applications. m-Tolylacetic acid is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules. | ||||||||||||||||||||
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m-Tolylacetic acid-d3 | m-Tolylacetic acid-d3 (3-Methylbenzeneacetic acid-d3) is the deuterium labeled m-Tolylacetic acid (HY-W053507). m-Tolylacetic acid is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules. | |||||||||||||||||||||
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4-Aminophenylacetic acid | 99.26% | 4-Aminophenylacetic acid is a kind of biological materials or organic compounds that are widely used in life science research. | ||||||||||||||||||||
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3-Methylbenzoic acid | 99.24% | 3-Methylbenzoic acid is a weakly acidic compound and an important intermediate for the synthesis of various chemicals, drugs and agrochemicals, including the insect repellent DEET. | ||||||||||||||||||||
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4-Hydroxyphenylacetic acid (Standard) | 99.24% | 4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2. IC50 & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1. | ||||||||||||||||||||
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3-Hydroxyphenylacetic acid | 99.03% | 3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders. | ||||||||||||||||||||
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3-Bromophenylacetic acid | 99.00% | 2-(3-Bromophenyl)acetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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3-Aminophenylacetic acid | 98.03% | 3-Aminophenylacetic acid is an organic compound. | ||||||||||||||||||||
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4-Chlorophenylacetic acid (Standard) | ≥98% | 4-Chlorophenylacetic acid (Standard) is the analytical standard of 4-Chlorophenylacetic acid (HY-W010062). This product is intended for research and analytical applications. 4-Chlorophenylacetic acid is an aromatase antagonist. 4-Chlorophenylacetic acid inhibits estrogen-induced breast tumorigenesis by blocking estrogen conversion. 4-Chlorophenylacetic acid also serves as the sole carbon and energy source for Pseudomonas sp. CBS3; it is degraded via dechlorination and aromatic ring cleavage pathways, and induces the synthesis of protocatechuate 2,3-dioxygenase. 4-Chlorophenylacetic acid can be applied to studies related to estrogen-induced breast tumors and bacterial degradation pathways. | ||||||||||||||||||||
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3-Methoxyphenylacetic acid (Standard) | ≥98% | 3-Methoxyphenylacetic acid (Standard) (m-Methoxyphenylacetic acid (Standard)) is the analytical standard of 3-Methoxyphenylacetic acid (HY-W015343). This product is intended for research and analytical applications. 3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid) is an endogenous fungal phytotoxin found in the culture filtrate of Rhizoctonia solani. 3-Methoxyphenylacetic acid induces wilting in soybean seedlings in a concentration-dependent manner and may be involved in R. solani non-enzymatic toxin-mediated impairment of plant function. 3-Methoxyphenylacetic acid is used in research on resistance to Rhizoctonia root rot. | ||||||||||||||||||||
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(R)-2-Amino-3-(m-tolyl)propanoic acid | 97.0% | (R)-2-Amino-3-(m-tolyl)propanoic acid is a phenylalanine derivative. | ||||||||||||||||||||
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2-(3-(Aminomethyl)phenyl)acetic acid | 2-(3-(Aminomethyl)phenyl)acetic acid is a PROTAC linker that can be used to synthesize DU-14 (PTP1B/TC-PTP PROTAC) (HY-164864). | |||||||||||||||||||||
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References
- [1]. Kumar U, et al. Diels-Alder polymerization between bis (cyclopentadienones) and acetylenes. A versatile route to new highly aromatic polymers[J]. Macromolecules, 1995, 28(1): 124-130.
- [2]. Woodroofe C C, et al. Anomalous Schmidt reaction products of phenylacetic acid and derivatives[J]. Journal of the Chemical Society, Perkin Transactions 2, 2000 (1): 55-59.
