623152-17-0
623152-17-0
Chemical Structure
BMS-582949
- CAS No.: 623152-17-0
- Formula:C22H26N6O2
- Molecular Weight:406.48
IUPAC Name: 4-((5-(cyclopropylcarbamoyl)-2-methylphenyl)amino)-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
InChIKey: GDTQLZHHDRRBEB-UHFFFAOYSA-N
SMILES: O=C(NCCC)C1=CN(N=CN=C2NC3=CC(C(NC4CC4)=O)=CC=C3C)C2=C1C
Biological Activity: BMS-582949 (compound 7k) is an orally active and highly selective p38α MAP kinase inhibitor, with IC50 values of 13 nM for p38α, and 50 nM for cellular TNFα. BMS-582949 can be used for research on rheumatoid arthritis[1].
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BMS-582949 | BMS-582949 (compound 7k) is an orally active and highly selective p38α MAP kinase inhibitor, with IC50 values of 13 nM for p38α, and 50 nM for cellular TNFα. BMS-582949 can be used for research on rheumatoid arthritis. | |||||||||||||||||||||
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