6251-64-5
Chemical Structure
Acolongifloroside K
- CAS No.: 6251-64-5
- Formula:C29H44O12
- Molecular Weight:584.65
InChIKey: LPMXVESGRSUGHW-PUBTVXBGSA-N
SMILES: OC[C@@]12[C@]3([H])[C@](CC[C@@]1(C[C@H](C[C@H]2O)O[C@H]4[C@@H]([C@@H]([C@@H]([C@@H](O4)C)O)O)O)O)([H])[C@@]5([C@](C[C@H]3O)([C@@H](C(CO6)=CC6=O)CC5)C)O
Biological Activity: Acolongifloroside K is a cardenolide toxin identified from the seeds of Strophanthus gratus. It exhibits acute cardiotoxicity, with acute toxicity comparable to that of Ouabain (HY-B1457). Acolongifloroside K is an active component in Maasai arrow poison prepared from Acokanthera schimperi. Acolongifloroside K can be used in studies related to cardiotoxicity and cardenolides[1][2].
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Acolongifloroside K | Acolongifloroside K is a cardenolide toxin identified from the seeds of Strophanthus gratus. It exhibits acute cardiotoxicity, with acute toxicity comparable to that of Ouabain (HY-B1457). Acolongifloroside K is an active component in Maasai arrow poison prepared from Acokanthera schimperi. Acolongifloroside K can be used in studies related to cardiotoxicity and cardenolides. | |||||||||||||||||||||
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References
- [1]. Cassels BK, et al. Analysis of a Maasai arrow poison. Journal of ethnopharmacology. 1985;14(2-3):273-81. [Content Brief]
- [2]. Geiger UP, et al. Die Cardenolide der Samen von Strophanthus gratus (Wall. et Hook.) Franch. 2. Mitteilung [The cardenolides of the seeds from Strophanthus gratus(Wall. et Hook.) Franch. 2. Communication]. Helv Chim Acta. 1967 Jan 31;50(1):179-93. German. [Content Brief]
