626-48-2
Chemical Structure
6-Methyluracil
Synonym(s): Pseudothymine
- CAS No.: 626-48-2
- Formula:C5H6N2O2
- Molecular Weight:126.11
IUPAC Name: 6-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: SHVCSCWHWMSGTE-UHFFFAOYSA-N
SMILES: O=C1NC(C=C(C)N1)=O
Biological Activity: 6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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6-Methyluracil | 99.69% | 6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo. | ||||||||||||||||||||
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6-Methyluracil (Standard) | ≥98% | 6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo. | ||||||||||||||||||||
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Uracil 4,5-13C2 | Uracil 4,5-13C2 is the 13C labeled Uracil. | |||||||||||||||||||||
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Methylthiouracil | 98.0% | Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2. | ||||||||||||||||||||
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Uracil-13C2,15N2 | Uracil-13C2,15N2 is the 13C-labeled and 15N-labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | |||||||||||||||||||||
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Uracil-13C | Uracil-13C is the 13C labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | |||||||||||||||||||||
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Uracil-13C4,15N2 | 98.0% | Uracil-13C4,15N2 is the 13C and 15N labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | ||||||||||||||||||||
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Uracil-d1-1 | Uracil-d1-1 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | |||||||||||||||||||||
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Thymine | 99.94% | Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a Km value of 2.2 μM, Ki of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg. | ||||||||||||||||||||
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Thymine-15N2 | Thymine-15N2 is the 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-13C | Thymine-13C is the 13C labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-13C5,15N,15N2 | Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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References
- [1]. Cromby CH, et, al. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. J Inherit Metab Dis. 1994;17(1):81-4. [Content Brief]
- [2]. Taran IP, et, al. [The antiradiation action of 6-methyluracil]. Radiobiologiia. Mar-Apr 1993;33(2):285-90. [Content Brief]