627085-15-8
627085-15-8
Chemical Structure
OT-551
- CAS No.: 627085-15-8
- Formula:C13H24ClNO3
- Molecular Weight:277.79
IUPAC Name: 1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl cyclopropanecarboxylate hydrochloride
InChIKey: BGEXDXBTNACMOP-UHFFFAOYSA-N
SMILES: CC1(C)CC(OC(C2CC2)=O)CC(C)(C)N1O.[H]Cl
Biological Activity: OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research[1][2].
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OT-551 | OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research. | |||||||||||||||||||||
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References
- [1]. Masaki Tanito, et al. Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats. Exp Eye Res. 2010 Jul;91(1):111-4. [Content Brief]
- [2]. S. A. Mousa, et al. Anti-Angiogenesis Efficacy of the Novel NF-B and Oxidative Stress Inhibitor, OT-551. ARVO Annual Meeting Abstract.
