634924-89-3
634924-89-3
Chemical Structure
ANR94
- CAS No.: 634924-89-3
- Formula:C9H13N5O
- Molecular Weight:207.23
IUPAC Name: 8-ethoxy-9-ethyl-9H-purin-6-amine
InChIKey: QUGDTMONBLMLLD-UHFFFAOYSA-N
SMILES: NC1=C2N=C(OCC)N(CC)C2=NC=N1
Biological Activity: ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease[1][2].
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ANR94 | 98.91% | ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease. | ||||||||||||||||||||
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ANR94 (Standard) | ≥98% | ANR94 (Standard) is the analytical standard of ANR94 (HY-103162). This product is intended for research and analytical applications. ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease. | ||||||||||||||||||||
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References
- [1]. Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4(6):1010-1019. [Content Brief]
- [2]. Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33(12):1550-1561. [Content Brief]
