63521-15-3
63521-15-3
Chemical Structure
Cefazedone sodium
- CAS No.: 63521-15-3
- Formula:C18H14Cl2N5NaO5S3
- Molecular Weight:570.43
IUPAC Name: (E)-2-(1-(4-fluorophenyl)ethylidene)hydrazine-1-carboxamide
InChIKey: KPHCAENKLGZHCB-VQZRABBESA-M
SMILES: CC1=NN=C(SCC2=C(C(O[Na])=O)N3[C@H](SC2)[C@H](NC(CN4C=C(Cl)C(C(Cl)=C4)=O)=O)C3=O)S1
Biological Activity: Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria[1][2].
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Cefazedone sodium | Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria. | |||||||||||||||||||||
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References
- [1]. Gao L, et al. A Pharmacokinetic and Pharmacodynamic Study on Intravenous Cefazedone Sodium in Patients with Community-acquired Pneumonia. Chin Med J (Engl). 2015 May 5;128(9):1160-4. [Content Brief]
- [2]. Bloom JC, et al. Cephalosporin-induced immune cytopenia in the dog: demonstration of erythrocyte-, neutrophil-, and platelet-associated IgG following treatment with cefazedone. Am J Hematol. 1988 Jun;28(2):71-8. [Content Brief]
