63585-09-1
63585-09-1
Chemical Structure
Foscarnet sodium
Synonym(s): Trisodium phosphonoformate; Phosphonoformic acid trisodium salt
- CAS No.: 63585-09-1
- Formula:CNa3O5P
- Molecular Weight:191.95
IUPAC Name: sodium phosphonatoformate
InChIKey: DFHAXXVZCFXGOQ-UHFFFAOYSA-K
SMILES: O=P(O[Na])(O[Na])C(O[Na])=O
Biological Activity: Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Foscarnet sodium | 98.0% | Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis. | ||||||||||||||||||||
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Foscarnet sodium (Standard) | ≥98% | Foscarnet (sodium) (Standard) is the analytical standard of Foscarnet (sodium). This product is intended for research and analytical applications. Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis. | ||||||||||||||||||||
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References
- [1]. Manischewitz JF, et al. Synergistic effect of ganciclovir and foscarnet on cytomegalovirus replication in vitro.Antimicrob Agents Chemother. 1990 Feb;34(2):373-5. [Content Brief]
- [2]. Oberg B, et al. Antiviral effects of phosphonoformate (PFA, foscarnet sodium).Pharmacol Ther. 1982;19(3):387-415. [Content Brief]
- [3]. Hakki M, et al. Moving Past Ganciclovir and Foscarnet: Advances in CMV Therapy.Curr Hematol Malig Rep. 2020 Jan 24. [Content Brief]
