639065-13-7
Chemical Structure
ATTO 590
- CAS No.: 639065-13-7
- Formula:C37H39ClN2O9
- Molecular Weight:691.17
InChIKey: RUJOZSWWNQUGKP-UHFFFAOYSA-N
SMILES: CC1=CC(C)(C)N(CC)C2=C1C=C(C(C3=CC=CC=C3C(O)=O)=C(C=C(C(C)=CC(C)(C)N4CC)C4=C5)C5=[O+]6)C6=C2.O=Cl(=O)([O-])=O.CC(O)=O
Biological Activity: ATTO 590 is a rhodamine-class fluorescent dye that can be used for labeling DNA, RNA, or proteins. ATTO 590 features strong absorption, high fluorescence quantum yield, and excellent thermal and photostability. ATTO 590 can be used in various technical detections such as single-molecule detection, flow cytometry (FACS), and fluorescence in situ hybridization (FISH) (λabs/λem = 593-594/622-624 nM)[1][2][3][4][5].
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ATTO 590 | ATTO 590 is a rhodamine-class fluorescent dye that can be used for labeling DNA, RNA, or proteins. ATTO 590 features strong absorption, high fluorescence quantum yield, and excellent thermal and photostability. ATTO 590 can be used in various technical detections such as single-molecule detection, flow cytometry (FACS), and fluorescence in situ hybridization (FISH) (λabs/λem = 593-594/622-624 nM). | |||||||||||||||||||||
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References
- [1]. Hirsch M, et al. Live cell imaging of duplex siRNA intracellular trafficking. Nucleic acids research. 2015 May 19;43(9):4650-60.
- [2]. Hafi N, et al. Fluorescence nanoscopy by polarization modulation and polarization angle narrowing. Nature methods. 2014 May;11(5):579-84.
- [3]. Meyer SA, et al. Super-resolution imaging of ciliary microdomains in isolated olfactory sensory neurons using a custom two-color stimulated emission depletion microscope. Journal of biomedical optics. 2016 Jun 01;21(6):66017.
- [4]. Sheu SH, et al. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. 2022 Sep 01;185(18):3390-3407.e18.
- [5]. Kumar SR, et al. TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling. Molecular Therapy. 2024 Feb 7;32(2):325-39. [Content Brief]
