64019-93-8
Chemical Structure
Dipivefrin hydrochloride
Synonym(s): Dipivefrine hydrochloride
- CAS No.: 64019-93-8
- Formula:C19H30ClNO5
- Molecular Weight:387.90
IUPAC Name: 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene bis(2,2-dimethylpropanoate) hydrochloride
InChIKey: VKFAUCPBMAGVRG-UHFFFAOYSA-N
SMILES: CNCC(C1=CC=C(OC(C(C)(C)C)=O)C(OC(C(C)(C)C)=O)=C1)O.Cl
Biological Activity: Dipivefrin hydrochloride is an α/β-adrenoceptor agonist and a prodrug of epinephrine. Dipivefrin hydrochloride regulates intraocular pressure by agonizing α/β-adrenoceptors and modulating the aqueous humor outflow pathway. Dipivefrin hydrochloride acts on neuroblastoma cells and downregulates glutamate-induced intracellular calcium levels. Dipivefrin hydrochloride is used in research related to α/β-adrenoceptor-mediated diseases, such as glaucoma[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Dipivefrin hydrochloride | 98.76% | Dipivefrin hydrochloride is an α/β-adrenoceptor agonist and a prodrug of epinephrine. Dipivefrin hydrochloride regulates intraocular pressure by agonizing α/β-adrenoceptors and modulating the aqueous humor outflow pathway. Dipivefrin hydrochloride acts on neuroblastoma cells and downregulates glutamate-induced intracellular calcium levels. Dipivefrin hydrochloride is used in research related to α/β-adrenoceptor-mediated diseases, such as glaucoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dipivefrin hydrochloride (Standard) | ≥98% | Dipivefrin hydrochloride (Standard) (Dipivefrine hydrochloride (Standard)) is the analytical standard of Dipivefrin hydrochloride (HY-B1323). This product is intended for research and analytical applications. Dipivefrin hydrochloride is an α/β-adrenoceptor agonist and a prodrug of epinephrine. Dipivefrin hydrochloride regulates intraocular pressure by agonizing α/β-adrenoceptors and modulating the aqueous humor outflow pathway. Dipivefrin hydrochloride acts on neuroblastoma cells and downregulates glutamate-induced intracellular calcium levels. Dipivefrin hydrochloride is used in research related to α/β-adrenoceptor-mediated diseases, such as glaucoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dipivefrin-d6 hydrochloride | 99.70% | Dipivefrin-d6 hydrochloride (Dipivefrine-d6 hydrochloride) is the deuterated-labeled Dipivefrin hydrochloride (HY-B1323). Dipivefrin hydrochloride is an α/β-adrenoceptor agonist and a prodrug of epinephrine. Dipivefrin hydrochloride regulates intraocular pressure by agonizing α/β-adrenoceptors and modulating the aqueous humor outflow pathway. Dipivefrin hydrochloride acts on neuroblastoma cells and downregulates glutamate-induced intracellular calcium levels. Dipivefrin hydrochloride is used in research related to α/β-adrenoceptor-mediated diseases, such as glaucoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Akaishi T, et al. Ocular hypotensive effects of anti-glaucoma agents in mice. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2009 Oct;25(5):401-8.
- [2]. Barak S, et al. Targeting the Reconsolidation of Licit Drug Memories to Prevent Relapse: Focus on Alcohol and Nicotine. International journal of molecular sciences. 2021 Apr 15;22(8):4090.
- [3]. Wu KY, et al. Effects of antiglaucoma drugs on cellular proliferation in cultured human corneal keratocytes. The Kaohsiung journal of medical sciences. 2006 Mar;22(3):120-5.
- [4]. Hong SJ, et al. Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2003 Jun;19(3):205-15.
