64058-48-6
64058-48-6
Chemical Structure
Spectinomycin sulfate hydrate
- CAS No.: 64058-48-6
- Formula:C14H34N2O15S
- Molecular Weight:502.49
InChIKey: OBZDRKHRQYPQDZ-SACNDDTHSA-N
SMILES: CN[C@@H]1[C@]2([H])[C@]([C@H]([C@@H]([C@@H]1O)NC)O)([H])O[C@@]3([H])[C@@](O2)(C(C[C@H](O3)C)=O)O.O=S(O)(O)=O.O.O.O.O
Biological Activity: Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM[1]-[5].
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Spectinomycin sulfate hydrate | Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM-. | |||||||||||||||||||||
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References
- [1]. Davies J, et al. Inhibition of protein synthesis by spectinomycin. Science. 1965 Sep 3;149(3688):1096-8. [Content Brief]
- [5]. Khan EA, et al. Safety evaluation study of lincomycin and spectinomycin hydrochloride intramuscular injection in chickens. Toxicol Rep. 2022 Jan 29;9:204-209. [Content Brief]
