64405-40-9
64405-40-9
Chemical Structure
CH-123
- CAS No.: 64405-40-9
- Formula:C14H18N2O5
- Molecular Weight:294.30
InChIKey: IRGLQUMAHASUTG-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C2N(C(CCC2CC(O)=O)C)C1=O)OCC
Biological Activity: CH-123 is an orally active lipid-lowering agent. CH-123 inhibits the elevated activities of β-glucuronidase, β-galactosidase, N-acetyl-β-glucosaminidase and acid phosphatase in aortic smooth muscle cells and hepatocytes. CH-123 reduces serum total lipid and cholesterol levels, as well as intracellular cholesterol content in aortic smooth muscle cells. CH-123 significantly inhibits lysosomal enzyme activity. CH-123 can be used in the research of atherosclerosis[1].
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CH-123 | CH-123 is an orally active lipid-lowering agent. CH-123 inhibits the elevated activities of β-glucuronidase, β-galactosidase, N-acetyl-β-glucosaminidase and acid phosphatase in aortic smooth muscle cells and hepatocytes. CH-123 reduces serum total lipid and cholesterol levels, as well as intracellular cholesterol content in aortic smooth muscle cells. CH-123 significantly inhibits lysosomal enzyme activity. CH-123 can be used in the research of atherosclerosis. | |||||||||||||||||||||
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