6481-48-7
Chemical Structure
1-Methylhistamine dihydrochloride
- CAS No.: 6481-48-7
- Formula:C6H13Cl2N3
- Molecular Weight:198.09
IUPAC Name: 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrochloride
InChIKey: AGXVEALMQHTMSW-UHFFFAOYSA-N
SMILES: NCCC1=CN(C)C=N1.[H]Cl.[H]Cl
Biological Activity: 1-Methylhistamine dihydrochloride is a histamine metabolite[1].
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1-Methylhistamine dihydrochloride | 99.89% | 1-Methylhistamine dihydrochloride is a histamine metabolite. | ||||||||||||||||||||
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1-Methylhistamine dihydrochloride (Standard) | 98.40% | 1-Methylhistamine dihydrochloride is a histamine metabolite. | ||||||||||||||||||||
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4-Methylhistamine dihydrochloride (Standard) | 4-Methylhistamine dihydrochloride (Standard) is the analytical standard of 4-Methylhistamine (dihydrochloride) (HY-107560). This product is intended for research and analytical applications. 4-Methylhistamine hydrochloride is the dihydrochloride salt of 4-Methylhistamine (HY-W580721). 4-Methylhistamine hydrochloride is a potent and selective agonist of histamine 4 receptor (H4R) with a Ki of 50 nM. 4-Methylhistamine hydrochloride has a >100-fold selectivity for the hH4R over the other histamine receptor subtypes. 4-Methylhistamine hydrochloride can potently activate the hH4R (pEC50 = 7.4). 4-Methylhistamine hydrochloride can be used for the researches of cancer, inflammation and immunology, such as lung cancer and sKin inflammation. | |||||||||||||||||||||
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3-Methylhistamine dihydrochloride (Standard) | ≥98% | 3-Methylhistamine (dihydrochloride) (Standard) is the analytical standard of 3-Methylhistamine (dihydrochloride). This product is intended for research and analytical applications. 3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice. | ||||||||||||||||||||
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1-Methylimidazoleacetic acid (Standard) | ≥98% | 1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) (Standard) is the analytical standard of 1-Methylimidazoleacetic acid. This product is intended for research and analytical applications. 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis. | ||||||||||||||||||||
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Histamine dihydrochloride (Standard) | 99.96% | Histamine dihydrochloride (Standard) is the analytical standard of Histamine dihydrochloride (HY-B0722). This product is intended for research and analytical applications. Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma. | ||||||||||||||||||||
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Betazole dihydrochloride | Betazole (Ametazole) dihydrochloride, a pyrazole analogue of histamine, is an orally active H2 receptor agonist. Betazole dihydrochloride induces gastric acid secretion, and causes an immediate and significant increase in common bile duct pressure. Betazole dihydrochloride has been used as a diagnostic agent known as histalog, for investigating gastric acid secretory capacity. | |||||||||||||||||||||
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1-Methyl-L-histidine | 99.97% | 1-Methyl-L-histidine is an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake. | ||||||||||||||||||||
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1-Methylhistamine-d3 dihydrochloride | 99.91% | 1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride). 1-Methylhistamine dihydrochloride is a histamine metabolite. | ||||||||||||||||||||
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1-Methyl-4-imidazoleacetic acid hydrochloride | 98.0% | 1-Methyl-4-imidazoleacetic acid hydrochloride is a stable metabolite of Histamine (HY-B1204) that is produced by the oxidation of the primary metabolite, N-methylhistamine. | ||||||||||||||||||||
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1-Methylhistamine | 1-Methylhistamine is a histamine (Him) metabolite. | |||||||||||||||||||||
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4-Methylhistamine hydrochloride | 4-Methylhistamine hydrochloride is the hydrochloride salt of 4-Methylhistamine (HY-W580721). 4-Methylhistamine hydrochloride is a potent and selective agonist of histamine 4 receptor (H4R) with a Ki of 50 nM. 4-Methylhistamine hydrochloride has a >100-fold selectivity for the hH4R over the other histamine receptor subtypes. 4-Methylhistamine hydrochloride can potently activate the hH4R (pEC50 = 7.4). 4-Methylhistamine hydrochloride can be used for the researches of cancer, inflammation and immunology, such as lung cancer and skin inflammation. | |||||||||||||||||||||
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