651055-83-3
651055-83-3
Chemical Structure
6-Amino-8-trifluoromethylphenanthridine
Synonym(s): 6A-8tFP
- CAS No.: 651055-83-3
- Formula:C14H9F3N2
- Molecular Weight:262.23
IUPAC Name: 8-(trifluoromethyl)phenanthridin-6-amine
InChIKey: VBQYJKNVRUTAHL-UHFFFAOYSA-N
SMILES: NC1=C2C=C(C(F)(F)F)C=CC2=C(C=CC=C3)C3=N1
Biological Activity: 6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site.
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6-Amino-8-trifluoromethylphenanthridine | 6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site. | |||||||||||||||||||||
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