659738-09-7
Chemical Structure
Micranoic acid B
- CAS No.: 659738-09-7
- Formula:C22H32O3
- Molecular Weight:344.50
IUPAC Name: 3-((3aS,3bS,6S,6aR,7aS,9aS)-3a,9a-dimethyl-1-oxo-6-(prop-1-en-2-yl)decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl)propanoic acid
InChIKey: YMWZSNQZURFZMX-RHSMJXSCSA-N
SMILES: C(CC(O)=O)[C@]12[C@]3([C@]([C@@]4(C)[C@](C)(CC3)C(=O)CC4)(CC[C@H]1C(C)=C)[H])C2
Biological Activity: Micranoic acid B is a terpenoid compound. Micranoic acid B exhibits cytotoxicity against cancer cells and shows comparable activity against multidrug-resistant and parental cancer cell lines. Micranoic acid B can be used for research on lung cancer, prostate cancer, and nasopharyngeal epidermoid carcinoma[1][2][3][4][5][6][7].
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Micranoic acid B | Micranoic acid B is a terpenoid compound. Micranoic acid B exhibits cytotoxicity against cancer cells and shows comparable activity against multidrug-resistant and parental cancer cell lines. Micranoic acid B can be used for research on lung cancer, prostate cancer, and nasopharyngeal epidermoid carcinoma. | |||||||||||||||||||||
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References
- [1]. Rao G, et al. α-Glucosidase and Bacterial β-Glucuronidase Inhibitors from the Stems of Schisandra sphaerandra Staph. Pharmaceuticals (Basel). 2022 Mar 9;15(3):329.
- [2]. Xiao WL, et al. Triterpenoids from the Schisandraceae family. Natural product reports. 2008 Oct;25(5):871-91. [Content Brief]
- [3]. Zou J, et al. Cycloartane triterpenoids from the stems of Schisandra glaucescens and their bioactivity. Fitoterapia. 2012 Jul;83(5):926-31.
- [4]. Lu Y, et al. Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens. Pharmaceutical biology. 2013 Sep;51(9):1204-7. [Content Brief]
- [5]. Shu L, et al. Rapid identification of chemical compositions of three species of Schisandra chinensis by ultra-high-performance liquid chromatography quadrupole-orbitrap-mass spectrometry. Journal of separation science. 2023 Oct;46(20):e2300466.
- [6]. He F, et al. Nortriterpene constituents from Schisandra sphenanthera. Tetrahedron. 2012 Jan 14;68(2):440-6.
- [7]. Li RT, et al. Micranoic acids A and B: two new octanortriterpenoids from Schisandra micrantha. Chemical & pharmaceutical bulletin. 2003 Oct;51(10):1174-6.