66104-22-1
66104-22-1
Chemical Structure
Pergolide
Synonym(s): LY127809 free base
- CAS No.: 66104-22-1
- Formula:C19H26N2S
- Molecular Weight:314.49
IUPAC Name: (6aR,9R,10aR)-9-((methylthio)methyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline
InChIKey: YEHCICAEULNIGD-MZMPZRCHSA-N
SMILES: [H][C@@]1(N(CCC)C[C@H](CSC)C[C@@]12[H])CC3=CNC4=CC=CC2=C43
Biological Activity: Pergolide (LY127809 free base), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptor agonist. Pergolide can be used for Parkinson's disease and hyperprolactinaemia research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pergolide | 99.68% | Pergolide (LY127809 free base), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptor agonist. Pergolide can be used for Parkinson's disease and hyperprolactinaemia research. | ||||||||||||||||||||
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Pergolide-d7 hydrochloride | Pergolide-d7 hydrochloride is deuterated labeled Pergolide (HY-13720). Pergolide (LY127809 (free base)) is an ergot-derived orally active dopamine receptor agonist. Pergolide can be used for Parkinson disease research. | |||||||||||||||||||||
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References
- [1]. S Franks, et al. Effectiveness of pergolide mesylate in long term treatment of hyperprolactinaemia. Br Med J (Clin Res Ed). 1983 Apr 9;286(6372):1177-9. [Content Brief]
- [2]. Daniela Uberti, et al. Pergolide protects SH-SY5Y cells against neurodegeneration induced by H(2)O(2). Eur J Pharmacol. 2002 Jan 2;434(1-2):17-20. [Content Brief]
