665013-76-3
665013-76-3
Chemical Structure
NDM-1 inhibitor-2
- CAS No.: 665013-76-3
- Formula:C9H9BrN4S
- Molecular Weight:285.16
IUPAC Name: 4-((3-bromobenzyl)amino)-2,4-dihydro-3H-1,2,4-triazole-3-thione
InChIKey: GVJZBRUKGHLCJD-UHFFFAOYSA-N
SMILES: S=C1NN=CN1NCC2=CC=CC(Br)=C2
Biological Activity: NDM-1 inhibitor-2 is an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) and has the ability to inhibit NDM-1 activity. NDM-1 inhibitor-2 exhibits a good inhibitory effect on drug-resistant bacterial strains that overexpress NDM-1. When NDM-1 inhibitor-2 is used in combination with the carbapenem antibiotic meropenem, a favorable synergistic effect can be produced[1].
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NDM-1 inhibitor-2 | NDM-1 inhibitor-2 is an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) and has the ability to inhibit NDM-1 activity. NDM-1 inhibitor-2 exhibits a good inhibitory effect on drug-resistant bacterial strains that overexpress NDM-1. When NDM-1 inhibitor-2 is used in combination with the carbapenem antibiotic meropenem, a favorable synergistic effect can be produced. | |||||||||||||||||||||
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