66640-87-7
66640-87-7
Chemical Structure
5-Hydroxytryptophol-d4
- CAS No.: 66640-87-7
- Formula:C10H7D4NO2
- Molecular Weight:181.22
IUPAC Name: 3-(2-hydroxyethyl-1,1,2,2-d4)-1H-indol-5-ol
InChIKey: KQROHCSYOGBQGJ-KHORGVISSA-N
SMILES: OC([2H])([2H])C([2H])([2H])C(C1=C2)=CNC1=CC=C2O
Biological Activity: 5-Hydroxytryptophol-d4 is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Hydroxytryptophol-d4 | 98.0% | 5-Hydroxytryptophol-d4 is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption. | ||||||||||||||||||||
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5-Hydroxytryptophol (Standard) | ≥98% | 5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse. | ||||||||||||||||||||
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5-Hydroxytryptophol | 99.84% | 5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse. | ||||||||||||||||||||
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5-Methoxytryptophol (Standard) | ≥98% | 5-Methoxytryptophol (Standard) is the analytical standard of 5-Methoxytryptophol. This product is intended for research and analytical applications. 5-Methoxytryptophol is a 5-methoxyindole alcohol structurally homologous to Melatonin (HY-B0075). It is secreted by the mammalian pineal gland and exhibits an inverse circadian rhythm. 5-Methoxytryptophol regulates bone metabolism by activating the ERK1/2 pathway. It reduces the levels of pro-inflammatory cytokines TNF-α and IL-1β, as well as proteolytic enzymes MMP-1 and MMP-2, in serum and dental pulp tissues, thereby ameliorating acute pulpitis. 5-Methoxytryptophol induces rapid sleep in mice, while high doses cause respiratory depression and death. 5-Methoxytryptophol. 5-Methoxytryptophol can be used in studies related to acute pulpitis, hypnosis, and bone metabolism. | ||||||||||||||||||||
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7-Ethyltryptophol (Standard) | ≥98% | 7-Ethyltryptophol (Standard) is the analytical standard of 7-Ethyltryptophol. This product is intended for research and analytical applications. | ||||||||||||||||||||
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α-Methylserotonin | α-Methylserotonin is a potent and selective agonist of 5-HT2 receptor. α-Methylserotonin is an analogue of serotonin formed in vivo from α-methyltryptophan. α-Methylserotonin mediates the lymphatic smooth muscle contraction and prevents the up-regulation of serotonin-receptor-mediated phosphoinositide hydrolysis. | |||||||||||||||||||||
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5-Hydroxyindoleacetaldehyde | 5-hydroxyindolacetaldehyde (5-HIAAld), an oxidation product of serotonin, is a tryptophan metabolite. 5-hydroxyindolacetaldehyde is formed from serotonin by monoamine oxidase A (MAO-A), | |||||||||||||||||||||
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4-Hydroxytryptophol | 4-Hydroxytryptophol is an in vitro metabolite of psilocin, can be found in human liver microsomes and recombinant monoamine oxidase A systems. 4-Hydroxytryptophol is not detected in in vivo samples from mice or humans. | |||||||||||||||||||||
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Serotonin | 99.76% | Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. | ||||||||||||||||||||
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Serotonin hydrochloride (Standard) | ≥98% | Serotonin (5-Hydroxytryptamine) (Standard) hydrochloride is the analytical standard of Serotonin hydrochloride (HY-B1473). This product is intended for research and analytical applications. Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. | ||||||||||||||||||||
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5-Hydroxyindole-3-acetic acid (Standard) | 98.14% | 5-Hydroxyindole-3-acetic acid (Standard) is the analytical standard of 5-Hydroxyindole-3-acetic acid. This product is intended for research and analytical applications. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. | ||||||||||||||||||||
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5-Hydroxyindole-3-acetic acid-13C6 | 5-Hydroxyindole-3-acetic acid-13C6 is the 13C-labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. | |||||||||||||||||||||
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Tryptophol (Standard) | 99.84% | Tryptophol (Standard) (Indole-3-ethanol (Standard)) is an analytical standard of Tryptophol (HY-W010155). This product is intended for use in research and analytical applications.Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces Apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy. | ||||||||||||||||||||
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