666837-93-0
666837-93-0
Chemical Structure
(E/Z)-SU9516
- CAS No.: 666837-93-0
- Formula:C13H11N3O2
- Molecular Weight:241.25
IUPAC Name: (E)-3-((1H-imidazol-5-yl)methylene)-5-methoxyindolin-2-one
InChIKey: QNUKRWAIZMBVCU-NYYWCZLTSA-N
SMILES: O=C1NC2=C(C=C(OC)C=C2)/C1=C\C3=CN=CN3
Biological Activity: (E/Z)-SU9516 is the isomer of SU9516 (HY-18629). SU9516 is a potent CDK2 inhibitor，with an IC50 of 22 nM，and also shows inhibitory effects on CDK1 and CDK4，with IC50s of 40，200 nM，respectively.
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(E/Z)-SU9516 | (E/Z)-SU9516 is the isomer of SU9516 (HY-18629). SU9516 is a potent CDK2 inhibitor，with an IC50 of 22 nM，and also shows inhibitory effects on CDK1 and CDK4，with IC50s of 40，200 nM，respectively. | |||||||||||||||||||||
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