667914-07-0
667914-07-0
Chemical Structure
VARS1-IN-2
- CAS No.: 667914-07-0
- Formula:C26H17N3O2S2
- Molecular Weight:467.56
InChIKey: LNFQOIRSFYOQCF-ATJXCDBQSA-N
SMILES: O=C(NC1=C/2C=CC=C1)C2=C3C(N4C(S\3)=NC5=C(CCC6=C5C=CC=C6)C4C7=CC=CS7)=O
Biological Activity: VARS1-IN-2 (Compound 2901) is a VARS1 inhibitor with a Kd of 0.014 µM. VARS1-IN-2 does not alter VARS1 expression either at mRNA or protein level. VARS1-IN-2 exerts anti-prostate cancer effects mainly through interfering VARS1’s tRNA aminoacylation activity but not its expression[1].
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VARS1-IN-2 | VARS1-IN-2 (Compound 2901) is a VARS1 inhibitor with a Kd of 0.014 µM. VARS1-IN-2 does not alter VARS1 expression either at mRNA or protein level. VARS1-IN-2 exerts anti-prostate cancer effects mainly through interfering VARS1’s tRNA aminoacylation activity but not its expression. | |||||||||||||||||||||
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