669076-03-3
669076-03-3
Chemical Structure
JNJ-26076713
- CAS No.: 669076-03-3
- Formula:C29H38N4O3
- Molecular Weight:490.64
IUPAC Name: (S)-4-(1-(3-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)propanoyl)piperidin-4-yl)-3-((S)-1,2,3,4-tetrahydroquinolin-3-yl)butanoic acid
InChIKey: AJVBWPQQXWRZHQ-BJKOFHAPSA-N
SMILES: O=C(C[C@@H]([C@H]1CNC2=C(C1)C=CC=C2)CC3CCN(CC3)C(CCC4=CC=C5CCCN=C5N4)=O)O
Biological Activity: JNJ-26076713 is a potent and orally active alpha V integrin antagonist with IC50 values of 2.3 nM and 6.3 nM for alpha(V)beta(3) and alpha(V)beta(5), respectively. JNJ-26076713 inhibits retinal neovascularization[1].
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JNJ-26076713 | JNJ-26076713 is a potent and orally active alpha V integrin antagonist with IC50 values of 2.3 nM and 6.3 nM for alpha(V)beta(3) and alpha(V)beta(5), respectively. JNJ-26076713 inhibits retinal neovascularization. | |||||||||||||||||||||
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