669764-17-4
669764-17-4
Chemical Structure
SU11606
- CAS No.: 669764-17-4
- Formula:C29H33ClN4O4S
- Molecular Weight:569.11
IUPAC Name: (Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(3-morpholinopropyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxoindoline-5-sulfonamide
InChIKey: JXOCDHNKTVLZLD-ITYLOYPMSA-N
SMILES: O=S(C1=CC2=C(C=C1)NC(/C2=C\C3=C(C(CCCN4CCOCC4)=C(N3)C)C)=O)(N(C)C5=CC=CC(Cl)=C5)=O
Biological Activity: SU11606 is a Met inhibitor, with an average IC50 of 0.17 μM. SU11606 shows inhibitory activity on Ron, FLK-1, with IC50s of 2.5 μM and 0.18 μM, respectively. SU11606 can be used in the research of tumors[1].
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SU11606 | SU11606 is a Met inhibitor, with an average IC50 of 0.17 μM. SU11606 shows inhibitory activity on Ron, FLK-1, with IC50s of 2.5 μM and 0.18 μM, respectively. SU11606 can be used in the research of tumors. | |||||||||||||||||||||
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