67025-98-3
Chemical Structure
β-Chlornaltrexamine dihydrochloride
Synonym(s): β-CNA dihydrochloride
- CAS No.: 67025-98-3
- Formula:C24H34Cl4N2O3
- Molecular Weight:540.35
IUPAC Name: (4R,4aS,7R,7aR,12bS)-7-(bis(2-chloroethyl)amino)-3-(cyclopropylmethyl)-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol dihydrochloride
InChIKey: JJZDLJGFHABVOM-QNWHWJQFSA-N
SMILES: O[C@]1([C@H]2C3)[C@@]4(CCN2CC5CC5)C6=C3C=CC(O)=C6O[C@@]4([H])[C@H](N(CCCl)CCCl)CC1.[H]Cl.[H]Cl
Biological Activity: β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is a potent long-term opioid receptor blocker. β-Chlornaltrexamine dihydrochloride can effectively block the inhibitory effect of κ opioid receptor agonists on dopamine release. β-Chlornaltrexamine dihydrochloride can be used to study the mechanism of pain perception[1].
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β-Chlornaltrexamine dihydrochloride | β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is a potent long-term opioid receptor blocker. β-Chlornaltrexamine dihydrochloride can effectively block the inhibitory effect of κ opioid receptor agonists on dopamine release. β-Chlornaltrexamine dihydrochloride can be used to study the mechanism of pain perception. | |||||||||||||||||||||
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