67227-55-8
67227-55-8
Chemical Structure
Primidolol
Synonym(s): UK-11443
- CAS No.: 67227-55-8
- Formula:C17H23N3O4
- Molecular Weight:333.38
IUPAC Name: 1-(2-((2-hydroxy-3-(o-tolyloxy)propyl)amino)ethyl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: RETPFDTUCPKFEC-UHFFFAOYSA-N
SMILES: O=C1NC(N(CCNCC(COC2=C(C)C=CC=C2)O)C=C1C)=O
Biological Activity: Primidolol (UK-11443), derived from Parmotrema perlatum, possesses antibacterial and antioxidant activities. Primidolol is also an orally active α/β Adrenergic Receptor blocker with antihypertensive activity. Primidolol can be used in research related to infections and cardiovascular diseases[1][2].
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Primidolol | Primidolol (UK-11443), derived from Parmotrema perlatum, possesses antibacterial and antioxidant activities. Primidolol is also an orally active α/β Adrenergic Receptor blocker with antihypertensive activity. Primidolol can be used in research related to infections and cardiovascular diseases. | |||||||||||||||||||||
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References
- [1]. Saltvedt E, et al. Effect of single and twice daily doses of primidolol (UK-11,443) in hypertension. Curr Med Res Opin. 1980;6(8):528-33. [Content Brief]
- [2]. Dwarakanath P R, et al. Profiling secondary metabolites from lichen “Parmotrema perlatum (Huds.) M. Choisy” and antibacterial and antioxidant potentials[J]. Biomass Conversion and Biorefinery, 2022: 1-11.
