674343-47-6
Chemical Structure
BMS-604992
Synonym(s): EX-1314
- CAS No.: 674343-47-6
- Formula:C24H32ClN7O5
- Molecular Weight:534.01
IUPAC Name: (S)-(3-(1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)(methyl)carbamate hydrochloride
InChIKey: DFDPBEQMMOYQHK-GMUIIQOCSA-N
SMILES: O=C(OCC1=CC=CC2=NN=C([C@H](NC(C(C)(N)C)=O)COCC3=CC=CC=C3)N12)N(CC(N)=O)C.[H]Cl
Biological Activity: BMS-604992 (EX-1314) is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 demonstrates high-affinity binding (Ki=2.3 nM) and potent functional activity (EC50=0.4 nM). BMS-604992 can stimulate food intake in rodents[1].
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BMS-604992 | BMS-604992 (EX-1314) is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 demonstrates high-affinity binding (Ki=2.3 nM) and potent functional activity (EC50=0.4 nM). BMS-604992 can stimulate food intake in rodents. | |||||||||||||||||||||
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