675103-36-3
675103-36-3
Chemical Structure
BAY-678
- CAS No.: 675103-36-3
- Formula:C20H15F3N4O2
- Molecular Weight:400.35
IUPAC Name: (R)-5-(5-acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidin-4-yl)picolinonitrile
InChIKey: PGIVGIFOWOVINL-GOSISDBHSA-N
SMILES: N#CC1=NC=C([C@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1
Biological Activity: BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BAY-678 | 98.66% | BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). | ||||||||||||||||||||
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BAY-678 (Standard) | ≥98% | BAY-678 (Standard) is the analytical standard of BAY-678 (HY-111457A). This product is intended for research and analytical applications. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). | ||||||||||||||||||||
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