67600-94-6
Chemical Structure
Hydrangenol 8-O-glucoside
Synonym(s): Hydrangenol 8-O-β-D-glucopyranoside
- CAS No.: 67600-94-6
- Formula:C21H22O9
- Molecular Weight:418.39
IUPAC Name: 3-(4-hydroxyphenyl)-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)isochroman-1-one
InChIKey: IKTPWMTZNXOEIV-VRKGAULQSA-N
SMILES: O=C1C(C(CC(C2=CC=C(O)C=C2)O1)=CC=C3)=C3O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO
Biological Activity: Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].
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Hydrangenol 8-O-glucoside | Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction. | |||||||||||||||||||||
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References
- [1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2. [Content Brief]
- [2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254. [Content Brief]
