67629-86-1
67629-86-1
Chemical Structure
IRBM-Z-1
- CAS No.: 67629-86-1
- Formula:C19H17F3N4O2
- Molecular Weight:390.36
InChIKey: PGKQTFPLIZHIIO-UHFFFAOYSA-N
SMILES: CC([N+]1=NOC([N-]C(NC2=CC=CC(C(F)(F)F)=C2)=O)=C1)CC3=CC=CC=C3
Biological Activity: IRBM-Z-1 is a non-competitive inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 1.8 μM. IRBM-Z-1 also exhibits inhibitory activity against the NS2B-NS3 proteases of T156I-mutated dengue virus 2 (DENV2) and West Nile virus (WNV), with IC50 values of 3.9 μM and 4.7 μM, respectively. IRBM-Z-1 inhibits ZIKV replication, attenuates virus-induced cytopathic effects. IRBM-Z-1 is applicable to research related to ZIKV infection[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IRBM-Z-1 | 98.61% | IRBM-Z-1 is a non-competitive inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 1.8 μM. IRBM-Z-1 also exhibits inhibitory activity against the NS2B-NS3 proteases of T156I-mutated dengue virus 2 (DENV2) and West Nile virus (WNV), with IC50 values of 3.9 μM and 4.7 μM, respectively. IRBM-Z-1 inhibits ZIKV replication, attenuates virus-induced cytopathic effects. IRBM-Z-1 is applicable to research related to ZIKV infection. | ||||||||||||||||||||
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