67814-76-0
Chemical Structure
Isepamicin sulfate
Synonym(s): Sch 21420 sulfate
- CAS No.: 67814-76-0
- Formula:C22H43N5O12.xH2SO4
- Molecular Weight:N/A
SMILES: O=S(O)(O)=O.O[C@@H]1[C@H]([C@@H](C[C@H](N)[C@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CN)NC([C@@H](O)CN)=O)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O.[x]
Biological Activity: Isepamicin sulfate (Sch 21420 sulfate) is a broad-spectrum aminoglycoside antibiotic. Isepamicin sulfate has considerable antimicrobial activity against some Gram-negative non-fermenting bacteria that are highly resistant to antibiotics. Isepamicin sulfate inhibits writhing reactions induced by Acetic acid (HY-Y0319), regulates vascular blood flow and blood pressure, and inhibits spontaneous uterine movements. Isepamicin sulfate has antidiuretic and blood sugar-raising effects. Isepamicin sulfate can be used in seizure research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isepamicin sulfate | 98.0% | Isepamicin sulfate (Sch 21420 sulfate) is a broad-spectrum aminoglycoside antibiotic. Isepamicin sulfate has considerable antimicrobial activity against some Gram-negative non-fermenting bacteria that are highly resistant to antibiotics. Isepamicin sulfate inhibits writhing reactions induced by Acetic acid (HY-Y0319), regulates vascular blood flow and blood pressure, and inhibits spontaneous uterine movements. Isepamicin sulfate has antidiuretic and blood sugar-raising effects. Isepamicin sulfate can be used in seizure research. | ||||||||||||||||||||
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References
- [1]. Samonis G, et al. Antimicrobial susceptibility of non-fermenting Gram-negative isolates to isepamicin in a region with high antibiotic resistance. Eur J Clin Microbiol Infect Dis. 2012 Nov;31(11):3191-8. [Content Brief]
- [2]. Shibata K, et al. [General pharmacological studies on isepamicin sulfate (HAPA-B)]. Jpn J Antibiot. 1987 Jan;40(1):145-69. [Content Brief]
