67824-72-0
67824-72-0
Chemical Structure
Alprenolol benzoate
- CAS No.: 67824-72-0
- Formula:C22H29NO4
- Molecular Weight:371.47
InChIKey: URFIUJMADXJBKL-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1)O.OC(CNC(C)C)COC2=C(CC=C)C=CC=C2
Biological Activity: Alprenolol benzoate is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol benzoate is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent[1][2][3].
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Alprenolol benzoate | Alprenolol benzoate is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol benzoate is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent. | |||||||||||||||||||||
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References
- [1]. Himori N, et al. Effects of beta-adrenoceptor blocking agents, pindolol, alprenolol and practolol on blood pressure and heart rate in conscious renal hypertensive dogs. Arch Int Pharmacodyn Ther. 1977 Jan;225(1):152-65. [Content Brief]
- [2]. Fernández-Guasti A, et al. Evidence for the involvement of the 5-HT1A receptor in the anxiolytic action of indorenate and ipsapirone. Psychopharmacology (Berl). 1990;101(3):354-8. [Content Brief]
- [3]. Parratt JR, et al. Myocardial and haemodynamic effects of the beta-adrenoceptor blocking drug alprenolol (H56/28) in anaesthetized cats. Br J Pharmacol. 1969 Oct;37(2):357-66. [Content Brief]
