681511-84-2
681511-84-2
Chemical Structure
SLW131
- CAS No.: 681511-84-2
- Formula:C21H27N5O5S
- Molecular Weight:461.53
InChIKey: FJTSRDJNSPTGCT-KRWDZBQOSA-N
SMILES: O=C(C1=CC=CC(NC(C(N[C@H](C(C)(C)C)C2=CC=C(O2)C)=N3)=NS3(=O)=O)=C1O)N(C)C
Biological Activity: SLW131 is a CCR7 antagonist with a Ki value of 9.85 nM. SLW131 inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM, and suppresses β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 serves as a probe for investigating the biological functions of CCR7 in cells. SLW131 is applicable to research related to rheumatoid arthritis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SLW131 | 99.97% | SLW131 is a CCR7 antagonist with a Ki value of 9.85 nM. SLW131 inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM, and suppresses β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 serves as a probe for investigating the biological functions of CCR7 in cells. SLW131 is applicable to research related to rheumatoid arthritis. | ||||||||||||||||||||
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