681514-83-0
Chemical Structure
CCR7 Ligand 1
Synonym(s): CCR7-Cmp2105
- CAS No.: 681514-83-0
- Formula:C22H29N5O5S
- Molecular Weight:475.56
IUPAC Name: (R)-3-((4-((2,2-dimethyl-1-(5-methylfuran-2-yl)propyl)amino)-1,1-dioxido-1,2,5-thiadiazol-3-yl)amino)-2-hydroxy-N,N,6-trimethylbenzamide
InChIKey: MAYXLCLBDVEYAL-SFHVURJKSA-N
SMILES: O=C(N(C)C)C1=C(C)C=CC(NC(C(N[C@@H](C2=CC=C(C)O2)C(C)(C)C)=N3)=NS3(=O)=O)=C1O
Biological Activity: CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCR7 Ligand 1 | 99.19% | CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM. | ||||||||||||||||||||
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