68324-95-8
Chemical Structure
Δ17-6-keto Prostaglandin F1α
Synonym(s): ω-3 6-keto PGF2α
- CAS No.: 68324-95-8
- Formula:C20H32O6
- Molecular Weight:368.46
IUPAC Name: 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,1E,5Z)-3-hydroxyocta-1,5-dien-1-yl)cyclopentyl)-6-oxoheptanoic acid
InChIKey: HFKNJQYMAGMXTR-CAPHXMBKSA-N
SMILES: O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](C/C=C\CC)O)CC(CCCCC(O)=O)=O
Biological Activity: Δ17-6-keto Prostaglandin F1α (Δ17-6-keto PGF1α) is a cyclooxygenase (COX) product of eicosapentaenoic acid (EPA) in various tissues such as seminal vesicles, lung, Polymorphonuclear leukocytes, and ocular tissues. Δ17-6-keto PGF1α and other 3-series COX products from EPA, such as PGF3α, PGE3, and thromboxane B3, may be involved in the reduced incidence of glaucoma in patients on a marine-rich (EPA-rich) diet.
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Δ17-6-keto Prostaglandin F1α | Δ17-6-keto Prostaglandin F1α (Δ17-6-keto PGF1α) is a cyclooxygenase (COX) product of eicosapentaenoic acid (EPA) in various tissues such as seminal vesicles, lung, Polymorphonuclear leukocytes, and ocular tissues. Δ17-6-keto PGF1α and other 3-series COX products from EPA, such as PGF3α, PGE3, and thromboxane B3, may be involved in the reduced incidence of glaucoma in patients on a marine-rich (EPA-rich) diet. | |||||||||||||||||||||
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