68593-96-4
68593-96-4
Chemical Structure
5-OH-DPAT
Synonym(s): 5-Hydroxy-DPAT
- CAS No.: 68593-96-4
- Formula:C16H25NO
- Molecular Weight:247.38
IUPAC Name: 6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
InChIKey: MDBWEQVKJDMEMK-UHFFFAOYSA-N
SMILES: OC1=CC=CC2=C1CCC(N(CCC)CCC)C2
Biological Activity: 5-OH-DPAT (5-Hydroxy-DPAT) is a potent and selective dopamine D2-receptor agonist lacking effects at 5-HT receptors. 5-OH-DPAT produces a moderate facilitation of the male rat sexual behavior[1][2].
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5-OH-DPAT | 5-OH-DPAT (5-Hydroxy-DPAT) is a potent and selective dopamine D2-receptor agonist lacking effects at 5-HT receptors. 5-OH-DPAT produces a moderate facilitation of the male rat sexual behavior. | |||||||||||||||||||||
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References
- [1]. Ahlenius S, et al. Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat. Naunyn Schmiedebergs Arch Pharmacol. 1989 May;339(5):551-6. [Content Brief]
- [2]. Karlsson A, et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): assessment of optical purities and dopaminergic activities. Chirality. 1990;2(2):90-5. [Content Brief]
