687627-78-7
687627-78-7
Chemical Structure
NOD1-IN-1
- CAS No.: 687627-78-7
- Formula:C16H14ClN3O3
- Molecular Weight:331.75
InChIKey: CEQUQTKEVIQAMX-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C=C1O)NC2=NC=NC3=CC(OC)=C(OC)C=C23
Biological Activity: NOD1/-IN-1 (Compound 2) is a potent RIPK2 inhibitor with an IC50 value of 0.65 nM determined by ADP-Glo assays. NOD1/-IN-1 selectively inhibits the NOD1 pathway (with an IC50 of 33 nM for NOD1), blocking the production of pro-inflammatory cytokines and thereby reducing inflammation. NOD1/-IN-1 is applicable for research in the field of colitis[1].
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NOD1-IN-1 | NOD1/-IN-1 (Compound 2) is a potent RIPK2 inhibitor with an IC50 value of 0.65 nM determined by ADP-Glo assays. NOD1/-IN-1 selectively inhibits the NOD1 pathway (with an IC50 of 33 nM for NOD1), blocking the production of pro-inflammatory cytokines and thereby reducing inflammation. NOD1/-IN-1 is applicable for research in the field of colitis. | |||||||||||||||||||||
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