6903-79-3
6903-79-3
Chemical Structure
Aplodan
Synonym(s): Creatinol O-phosphate; Creatinol phosphate; Creatinolfosfate
- CAS No.: 6903-79-3
- Formula:C4H12N3O4P
- Molecular Weight:197.13
IUPAC Name: 2-(1-methylguanidino)ethyl dihydrogen phosphate
InChIKey: FOIPWTMKYXWFGC-UHFFFAOYSA-N
SMILES: N=C(N)N(C)CCOP(O)(O)=O
Biological Activity: Aplodan (Creatinol O-phosphate) is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or acute myocardial infarction [1][2][3][4][5][6].
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Aplodan | 99.20% | Aplodan (Creatinol O-phosphate) is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or acute myocardial infarction . | ||||||||||||||||||||
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Aplodan (Standard) | Aplodan (Standard) (Creatinol O-phosphate (Standard)) is the analytical standard of Aplodan (HY-107335). This product is intended for research and analytical applications. Aplodan (Creatinol O-phosphate) is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or acute myocardial infarction . | |||||||||||||||||||||
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References
- [1]. Olsen JI, et al. A 31P NMR spectroscopy study of Xenopus laevis heart perfused in vitro with creatinol-O-phosphate, phosphocreatine, adenosine triphosphate, fructose diphosphate and ouabain. Pharmacol Res. 1993 Sep;28(2):135-51. [Content Brief]
- [2]. Botti G, et al. Preliminary report on electrophysiological effectiveness of creatinol O-phosphate (COP) in human subjects. Arzneimittelforschung. 1979;29(9a):1491-1494. [Content Brief]
- [3]. Di Maio F, et al. Activity of creatinol O-phosphate on persistent ventricular premature beats in ischemic heart disease. Double blind clinical trial. Arzneimittelforschung. 1979;29(9a):1488-1490. [Content Brief]
- [4]. Knippel M, et al. Effects of creatinol O-phosphate on serum enzymes in acute myocardial infarction. Arzneimittelforschung. 1979;29(9a):1480-2. [Content Brief]
- [5]. Godfraind T, et al. An analysis of the reduction by creatinol O-phosphate of the myocardial lesions evoked by isoprenaline in the rat. Arzneimittelforschung. 1979;29(9a):1457-64. [Content Brief]
- [6]. Marchetti G, et al. Effects of creatinol-O-phosphate (COP) on haemodynamics and cardiac metabolism in conscious and anaesthetized dogs. Arzneimittelforschung. 1978;28(10):1708-11. [Content Brief]
