693823-79-9
693823-79-9
Chemical Structure
AMG-076 free base
- CAS No.: 693823-79-9
- Formula:C26H33F3N2O2
- Molecular Weight:462.55
IUPAC Name: 1-(2-((4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-3,4,4a,5,11,11a-hexahydro-1H-pyrido[4,3-b]carbazol-2(6H)-yl)ethyl)cyclohexanecarboxylic acid
InChIKey: WAOZNBXSEVIAGX-MBOZVWFJSA-N
SMILES: O=C(C1(CCN2CC[C@]3([H])CC(NC4=C5C=C(C(F)(F)F)C=C4)=C5[C@H](C)[C@@]3([H])C2)CCCCC1)O
Biological Activity: AMG-076 free base is an orally bioavailable and selective MCHR1 antagonist. AMG-076 free base results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice[1].
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AMG-076 free base | AMG-076 free base is an orally bioavailable and selective MCHR1 antagonist. AMG-076 free base results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice. | |||||||||||||||||||||
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