70842-04-5
Chemical Structure
Ro 13-3978
- CAS No.: 70842-04-5
- Formula:C12H10F4N2O2
- Molecular Weight:290.22
IUPAC Name: 3-(4-fluoro-3-(trifluoromethyl)phenyl)-5,5-dimethylimidazolidine-2,4-dione
InChIKey: BTGSGTWRNQCEQY-UHFFFAOYSA-N
SMILES: O=C1NC(C(=O)N1C2=CC=C(F)C(=C2)C(F)(F)F)(C)C
Biological Activity: Ro 13-3978 is an orally active antischistosomal agent. Ro 13-3978 exhibits excellent in vivo antischistosomal activity against juvenile and adult Schistosoma mansoni infections. Ro 13-3978 shows no in vivo activity against E. caproni and F. hepatica. Ro 13-3978 blocks dihydrotestosterone-induced proliferation of androgen-dependent cells. Ro 13-3978 can be used in research related to schistosomiasis[1][2].
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Ro 13-3978 | Ro 13-3978 is an orally active antischistosomal agent. Ro 13-3978 exhibits excellent in vivo antischistosomal activity against juvenile and adult Schistosoma mansoni infections. Ro 13-3978 shows no in vivo activity against E. caproni and F. hepatica. Ro 13-3978 blocks dihydrotestosterone-induced proliferation of androgen-dependent cells. Ro 13-3978 can be used in research related to schistosomiasis. | |||||||||||||||||||||
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