70968-04-6
Chemical Structure
Suc-Ala-Ala-Pro-Leu-pNA
Synonym(s): N-Succinyl-AAPL-p-nitroanilide
- CAS No.: 70968-04-6
- Formula:C27H38N6O9
- Molecular Weight:590.63
IUPAC Name: 4-(((S)-1-(((S)-1-((S)-2-(((S)-4-methyl-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)amino)-4-oxobutanoic acid
InChIKey: PTHRPHGMGFMCSS-USNOLKROSA-N
SMILES: O=C(O)CCC(N[C@@H](C)C(N[C@@H](C)C(N1[C@H](C(N[C@@H](CC(C)C)C(NC2=CC=C([N+]([O-])=O)C=C2)=O)=O)CCC1)=O)=O)=O
Biological Activity: Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia[1].
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Suc-Ala-Ala-Pro-Leu-pNA | 99.81% | Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia. | ||||||||||||||||||||
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